FDA approved drug targets, Metabolic proteins
Intracellular
Group enriched (Spermatocytes, Early spermatids, Late spermatids)
Not detected in immune cells
Not detected
Forms a complex composed of a calmodulin-dependent catalytic subunit (also known as calcineurin A) and a regulatory Ca(2+)-binding subunit (also known as calcineurin B). There are three catalytic subunits, each encoded by a separate gene (PPP3CA, PPP3CB, and PPP3CC) and two regulatory subunits which are also encoded by separate genes (PPP3R1 and PPP3R2) (By similarity). Interacts with SPATA33 (via PQIIIT motif) (PubMed:34446558).
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For Research Use Only. Not For Clinical Use.