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PRDX4
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Protein class
Cancer-related genes, Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Plasma cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer; disulfide-linked, upon oxidation (PubMed:9388242). 5 homodimers assemble to form a ring-like decamer (PubMed:21994946). Can form heterodimers with PRDX1 (PubMed:9388242).
Molecular function
Antioxidant, Oxidoreductase, Peroxidase
More Types Infomation
- Mouse Anti-PRDX4 Recombinant Antibody (clone SAIC-40A-24) (FAMAB-1521CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Immuno-MRM, WB, ELISA
- Mouse Anti-PRDX4 Recombinant Antibody (clone SAIC-40C-8) (FAMAB-1517CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Immuno-MRM, WB, ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P
- Mouse Anti-PRDX4 Antibody (clone SAIC-40A-24), mRNA (FAMAB-1521CQ-mRNA)
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- Species Reactivity: Human
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
- Mouse Anti-PRDX4 Antibody (clone SAIC-40C-8), mRNA (FAMAB-1517CQ-mRNA)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.