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RAB11FIP3
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Proximal tubular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Interacts with RAB11B, RAB25 and RAB11FIP4. Interacts with ARF6; according to PubMed:16148947, it specifically interacts with ARF6 but not ARF5. Interacts with ARF6; according to PubMed:17030804 but not PubMed:16148947. Interacts with RACGAP1/MgcRacGAP; interaction takes place during late stage of cytokinesis and is required for recruitment to the midbody. Interacts with ASAP1 and EXOC7. Interacts with dynein intermediate chain and dynactin (DCTN1) (PubMed:25035494).
More Types Infomation
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2a, κ
- Application: WB, IP, ELISA
- Recombinant Anti-Human RAB11FIP3 Antibody scFv Fragment (MOB-2789z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, IHC, FuncS
- Recombinant Anti-Human RAB11FIP3 Antibody Fab Fragment (MOB-2789z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, Neut, FuncS
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For Research Use Only. Not For Clinical Use.