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RAP2B
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008]
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Urothelial cells, Squamous epithelial cells, Basal squamous epithelial cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A (By similarity).
Molecular function
Hydrolase
More Types Infomation
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- Species Reactivity: Human
- Application: ICC/IF, IHC-P, WB
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For Research Use Only. Not For Clinical Use.