Disease related genes, Human disease related genes, Plasma proteins
Intracellular
Cell type enhanced (Cytotrophoblasts)
Low immune cell specificity
Low cell line specificity
Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex either with RFC1 or with RAD17. The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated by PCNA. RFC2 also interacts with PRKAR1A; the complex may be involved in cell survival (PubMed:15655353). Interacts with DDX11 (PubMed:18499658).
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For Research Use Only. Not For Clinical Use.