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RFC4

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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
IP, WB
Species Reactivity:
Human
Application:
WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, Dot, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
RIA, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, IP, FuncS
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