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RGS19

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (NK-cells, Hofbauer cells, Kupffer cells, Macrophages, B-cells, monocytes, dendritic cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HMC-1, NB-4, THP-1)

Interaction

Interacts with GIPC PDZ domain.

Molecular function

Signal transduction inhibitor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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