Enzymes, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (dendritic cells, Cytotrophoblasts, Pancreatic endocrine cells)
Immune cell enhanced (plasmacytoid DC)
Low cell line specificity
Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells which transiently dissociates following mitogenic stimulation. Also associates with MAPK14/p38-alpha. Activated RPS6KA4 associates with and phosphorylates the NF-kappa-B p65 subunit RELA.
Kinase, Serine/threonine-protein kinase, Transferase
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For Research Use Only. Not For Clinical Use.