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S100A11

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Pancreatic endocrine cells, Urothelial cells, Extravillous trophoblasts, Basal respiratory cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Low cell line specificity

Interaction

Homodimer; disulfide-linked.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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