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SCG2

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Enteroendocrine cells, Bipolar cells, Ionocytes, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC TERT1, HSkMC, hTERT-RPE1, SCLC-21H, SH-SY5Y, WM-115)

Interaction

Interacts with Secretogranin III/SCG3.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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