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SDC4

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22.
Protein class

Cancer-related genes, Transporters

Predicted location

Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Exocrine glandular cells, Pancreatic endocrine cells, Suprabasal keratinocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HBEC3-KT)

Interaction

Homodimer. Interacts (via its cytoplasmic domain) with GIPC (via its PDZ domain). Interacts (via its cytoplasmic domain) with NUDT16L1 (By similarity). Interacts with CDCP1 and SDCBP.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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