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SEPT3
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Extravillous trophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, Daudi, SCLC-21H)
Interaction
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.