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SFRP4

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Endometrial stromal cells, Fibroblasts, Peritubular cells, Granulosa cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC diff, HSkMC, U-937)

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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