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SFRP5

Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008]
Predicted location

Secreted

Single cell type specificity

Cell type enriched (Cholangiocytes)

Immune cell specificity

Immune cell enriched (naive CD8 T-cell)

Cell line specificity

Cell line enhanced (A549, CACO-2, RPMI-8226, SCLC-21H)

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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