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SLC18A2
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]
Protein class
Disease related genes, FDA approved drug targets, Metabolic proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enriched (granulocytes)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enriched (HMC-1)
Interaction
Interacts with SLC6A3.
More Types Infomation
-
- Species Reactivity: Human
- Application: IHC-P, WB
- Recombinant Human Anti-human SLC18A2 Antibody scFv Fragment (MHH-909-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: RIA, WB, FuncS
- Recombinant Human Anti-human SLC18A2 Antibody Fab Fragment (MHH-909-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, Neut, FuncS
- Recombinant Anti-human SLC18A2 Antibody scFv Fragment (MOB-909-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, Neut, FuncS
- Recombinant Anti-human SLC18A2 Antibody Fab Fragment (MOB-909-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, IF, FuncS
- Recombinant Anti-human SLC18A2 Antibody (MOB-909)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FuncS
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For Research Use Only. Not For Clinical Use.