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SLC1A3
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Astrocytes, Muller glia cells, Microglial cells, Oligodendrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Group enriched (myeloid DC, classical monocyte, intermediate monocyte)
Cell line specificity
Cell line enhanced (AF22, CACO-2, HaCaT)
Interaction
Homotrimer (PubMed:28424515). Interacts with isoform 2 of BSG (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-Fr, IHC-P
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
-
- Derivation: Phage display library screening
- Species Reactivity: Mouse
- Type: IgG
- Application: WB, IHC-P
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.