Disease related genes
Intracellular
Cell type enhanced (Astrocytes, Early spermatids, Inhibitory neurons, Endometrial stromal cells, Oligodendrocyte precursor cells)
Immune cell enriched (basophil)
Cell line enhanced (AF22, BJ hTERT+, HBF TERT88, OE19, RPMI-8226)
Homodimer (Probable). Heterodimer of isoform 1 and isoform 2 (Probable). Interacts with SIAH1, SIAH2, SNCA, RNF19A AND PRKN. Isoform 2 has a strong tendency to form aggregates and can sequester isoform 1.
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For Research Use Only. Not For Clinical Use.