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SNX18
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Granulosa cells, Kupffer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer with SNX9 (PubMed:20427313). Interacts with ITCH (PubMed:20491914). Interacts with dynamin-2 (DNM2), SYNJ1 and WASL (PubMed:20427313, PubMed:29437695). Interacts with the AP-1 complex (PubMed:18411244). Interacts with FCHSD1 (via the F-BAR domain) (By similarity).
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.