Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
Loading...
Custom Services order now ship next day

STAT5B

Engineered Antibody
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
STAT5B
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2)

Interaction

Upon activation, forms homodimers (PubMed:29844444). Forms also heterodimers with related family members. Binds NR3C1 (By similarity). Interacts with NCOA1 (PubMed:12954634). Interacts with NMI (PubMed:9989503). Interacts with SOCS7 (PubMed:15677474). Interacts (via SH2 domain) with INSR (PubMed:9428692). Interacts with CPEB3; this inhibits STAT5B-mediated transcriptional activation (PubMed:20639532).

Molecular function

Activator, DNA-binding

More Types Infomation
Related Diseases
Endometrial Cancer Endometrial Cancer
Non-small Cell Lung Cancer Non-small Cell Lung Cancer
Pancreatic Cancer Pancreatic Cancer
Throid Cancer Throid Cancer
AGE-RAGE Signaling Pathway in Diabetic Complications AGE-RAGE Signaling Pathway in Diabetic Complications
Related Signaling Pathways
ErbB Signaling Pathway ErbB Signaling Pathway
MAPK Signaling Pathway MAPK Signaling Pathway

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart
    Inquiry

    Go to compare