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STMN2

STMN2 (Stathmin 2) is a Protein Coding gene. This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Diseases associated with STMN2 include Goldberg-Shprintzen Syndrome and Kuru.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Excitatory neurons, Horizontal cells, Inhibitory neurons, Rod photoreceptor cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enriched (SH-SY5Y)

Interaction

Interacts with MAPK8 (By similarity). Interacts with ITM2C. Interacts with KIFBP. Interacts (via the N-terminal region) with CIB1 (via C-terminal region); the interaction is direct, occurs in a calcium-dependent manner and attenuates the neurite outgrowth inhibition of STMN2.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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