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STMN3

This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Granulosa cells, Horizontal cells, Bipolar cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (AN3-CA, MOLT-4, REH, SCLC-21H, SH-SY5Y)

Interaction

Interacts with STAT3. Interacts with CLU (secreted form); this interaction may act as an important modulator during neuronal differentiation (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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