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Stx2

Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, whose genes are considered to be part of the genome of lambdoid prophages. The toxins are named for Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli (STEC), which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC).
Protein class

Cancer-related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Early spermatids, Late spermatids, Endometrial ciliated cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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