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STX6

STX6 (Syntaxin 6) is a Protein Coding gene. Diseases associated with STX6 include tauopathy. Among its related pathways are Normal wtCFTR traffic / ER-to-Golgi and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX10.
Protein class

Plasma proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (PubMed:17159904). Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2; the interaction promotes MARCHF2-mediated ubiquitination and degradation of CFTR (PubMed:23818989). Interacts with MARCHF3 (By similarity). Interacts with GOPC (PubMed:11384996). Interacts with UHRF1BP1L (via C-terminal coiled-coil domain) (PubMed:20163565). Interacts with BAIAP3; this interaction is increased in the presence of calcium (PubMed:28626000).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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