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TBL1Y
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Squamous epithelial cells, Basal squamous epithelial cells, Inhibitory neurons, Urothelial cells, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (U-698)
Interaction
Probable component of the N-Cor repressor complex and some E3 ubiquitin ligase complex. Interacts with NCOR2 (PubMed:30341416).
Molecular function
Activator
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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- Species Reactivity: Human, Mouse, Porcine, Rat, Dog
- Type: Mouse IgG2b
- Application: ELISA, WB, ICC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.