Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Intracellular
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Microglial cells, Inhibitory neurons)
Low immune cell specificity
Low cell line specificity
Efficient DNA binding requires dimerization with another bHLH protein. Forms homo- or heterooligomers with myogenin, E12 and ITF2 proteins. Interacts with PTF1A. Interacts with NEUROD2 (By similarity). Interacts with RUNX1T1. Interacts with AML1-MTG8/ETO (via nervy homology region 2 in oligomerized form) (PubMed:23812588). Interacts with BHLHA9 (PubMed:25466284).
Developmental protein, DNA-binding
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For Research Use Only. Not For Clinical Use.