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tgt

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For Research Use Only. Not For Clinical Use.


Background

tgt, or Queuine tRNA-ribosyltransferase, is an enzyme that catalyzes the exchange of guanine for queuine (a hypermodified nucleoside) at position 34 (wobble position) in specific tRNAs (e.g., tRNA-Asp, tRNA-Asn). This modification is crucial for accurate translation and reading of certain codons, impacting protein synthesis efficiency.
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