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Thrombin

The coagulation is a complex signal cascade, thrombin (Thrombin) in which a central place. Thrombin circulation system fibrinogen degradation fibrin monomer (which can polymerize to form fibrin blood clots fiber matrix), there are many cells directly regulated. As a serine protease, which triggers platelet deformed, release of platelet activator ADP, serotonin and thromboxane firing A2, and chemokines, and growth factors.

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