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Thsd1
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Protein class
Disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Endothelial cells, Astrocytes, Adipocytes, Spermatocytes, Microglial cells, Hepatic stellate cells, Basal respiratory cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (fHDF/TERT166, HBEC3-KT, hTCEpi, hTERT-HME1, HUVEC TERT2, LHCN-M2)
Interaction
Part of a complex composed of THSD1, PTK2/FAK1, TLN1 and VCL (PubMed:29069646). Interacts with TLN1 (PubMed:27895300, PubMed:29069646).
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