Intracellular
Cell type enhanced (Pancreatic endocrine cells)
Low immune cell specificity
Cell line enhanced (CACO-2)
Component of the BCR(TNFAIP1) E3 ubiquitin ligase complex, at least composed of CUL3, TNFAIP1/BACURD2 and RBX1. Interacts with RHOA; with a preference for RhoA-GDP. Interacts with RHOB. Interacts with PCNA. Interacts with CSNK2B.
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For Research Use Only. Not For Clinical Use.