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TREML2
TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008]
Protein class
Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Late spermatids, Early spermatids, Syncytiotrophoblasts, B-cells)
Immune cell specificity
Immune cell enhanced (neutrophil, naive B-cell)
Cell line specificity
Cell line enhanced (HEL, HL-60, JURKAT, SuSa, U-698, U-937)
Interaction
Interacts with CD276 and this interaction enhances T-cell activation.
Molecular function
Receptor
More Types Infomation
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.