Intracellular
Cell type enhanced (B-cells, Gastric mucus-secreting cells, Squamous epithelial cells, T-cells, Basal squamous epithelial cells, Macrophages)
Low immune cell specificity
Cell line enhanced (BEWO, SK-BR-3)
Homotrimer. Interacts (via the B30. 2/SPRY domain) with HIV-1 capsid complexes (PubMed:17156811). Interacts (via B-box and SPRY domain) with TRIM5 (PubMed:21680743, PubMed:17156811).
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For Research Use Only. Not For Clinical Use.