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TRIO

This polyclonal antibody against Trio sequence is specific and more sensitive than the available commercial antibodies against Trio. This antibody can be used to test whether Trio can be a prognosis marker of different types of tumors.
Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Group enriched (Oligodendrocyte precursor cells, Inhibitory neurons, Excitatory neurons, Microglial cells, Astrocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (U-87 MG)

Interaction

Interacts with CARMIL1 (PubMed:19846667). Interacts with PTPRF/LAR (PubMed:8643598). Interacts with ANKRD26 (PubMed:22666460). Interacts with Bassoon/BSN and Piccolo/PCLO (By similarity). Interacts with the cytoplasmic region of the heterodimer formed by NGFR and SORCS2. ProNGF binding mediates dissociation of TRIO from the receptor complex (PubMed:22155786).

Molecular function

Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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