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TYRO3
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Peritubular cells, Oligodendrocytes, Leydig cells, Excitatory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (BEWO)
Interaction
Monomer and homodimer. Interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 (By similarity). Interacts with PIK3R1; this interaction increases PI3-kinase activity (By similarity).
Molecular function
Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IF, WB
- Human Anti-TYRO3 Recombinant Antibody (clone 2412); scfv Fragment (HPAB-1527LY-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2411); Fab Fragment (HPAB-1526LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2717); Fab Fragment (HPAB-1525LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2710); Fab Fragment (HPAB-1524LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2411); scfv Fragment (HPAB-1526LY-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2717); scfv Fragment (HPAB-1525LY-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2710); scfv Fragment (HPAB-1524LY-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2717) (HPAB-1525LY)
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2710) (HPAB-1524LY)
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2709); Fab Fragment (HPAB-0028-DJB-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2414); Fab Fragment (HPAB-0027-DJB-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2718); Fab Fragment (NS-097CN-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-TYRO3 Recombinant Antibody (clone 2410); Fab Fragment (NS-096CN-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
- Human Anti-TYRO3 Recombinant Antibody (clone 2709); scFv Fragment (HPAB-0028-DJB-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2414); scFv Fragment (HPAB-0027-DJB-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-TYRO3 Recombinant Antibody (clone 2709) (HPAB-0028-DJB)
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
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