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ULK2
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Inhibitory neurons, Late spermatids, Excitatory neurons, Spermatocytes)
Immune cell specificity
Group enriched (intermediate monocyte, non-classical monocyte)
Cell line specificity
Cell line enhanced (SuSa)
Interaction
Interacts with SYNGAP1 (By similarity). Component of a complex consisting of ATG13/KIAA0652, ULK1 and RB1CC1/FIP200. Interacts (via C-terminus) with ATG13/KIAA0652. Associates with the mammalian target of rapamycin complex 1 (mTORC1) through an interaction with RPTOR.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
- Recombinant Mouse Anti-Human ULK2 Antibody (MOB-1235MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Mouse Anti-ULK2 Recombinant Antibody (VS3-WK1055) (VS3-WK1055)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.