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UPK3A

This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
Protein class

Disease related genes, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Prostatic glandular cells, Proximal enterocytes, Urothelial cells, monocytes, Basal prostatic cells)

Immune cell specificity

Immune cell enhanced (myeloid DC)

Cell line specificity

Group enriched (Hep G2, RT4)

Interaction

Heterodimer with uroplakin-1B (UPK1B).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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