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USP11
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008]
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Bipolar cells, Horizontal cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:24724799). Associated component of the Polycomb group (PcG) multiprotein PRC1-like complex (PubMed:20601937). Interacts with RANBP9/RANBPM (PubMed:12084015). Interacts with BRCA2 (PubMed:15314155). Interacts with CHUK/IKKA (PubMed:17897950). Interacts with NFKBIA (PubMed:19874889). Interacts with SPRY3, RAE1, MYCBP2/PAM, and KCTD6 (PubMed:29293652). (Microbial infection) Interacts with papilloma virus protein 16E7 (PubMed:18408009).
Molecular function
Hydrolase, Protease, Thiol protease
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Rabbit Anti-USP11 Recombinant Antibody (clone JM33-62) (MRO-1560-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP, FC
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IP
- Recombinant Mouse Anti-USP11 Antibody (clone 2D7A11) (VS3-FY1527)
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- Type: Mouse IgG1, κ
- Application: ELISA, WB, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC
- Mouse Anti-USP11 Recombinant Antibody (VS3-CJ1023) (VS3-CJ1023)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.