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USP28
The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes, NK-cells, Excitatory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with ZNF304 (PubMed:24623306). Interacts with PRKD1 (PubMed:24623306). Interacts with TP53BP1 (PubMed:16901786). Interacts with isoform 1 of FBXW7; following DNA damage, dissociates from FBXW7 leading to degradation of MYC (PubMed:17873522, PubMed:17558397).
Molecular function
Hydrolase, Protease, Thiol protease
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Rabbit Anti-USP28 Polyclonal Antibody (MRO-2260-CN) (MRO-2260-CN)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
- Recombinant Human Anti-USP28 Soluble TCR (BE2) (C-Cys) (VS-0622-YF5307)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Recombinant Human Anti-USP28 Soluble TCR (BA3) (C-Cys) (VS-0622-YF5306)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Human Anti-USP28 Recombinant Soluble TCR (clone BE2) (scTCR-1310YC-S(P))
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Human Anti-USP28 Recombinant Soluble TCR (clone BA3) (scTCR-1309YC-S(P))
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Recombinant Human Anti-USP28 Soluble TCR (BE2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2599)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Recombinant Human Anti-USP28 Soluble TCR (BA3) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2598)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF
- Recombinant Human Anti-USP28 Soluble TCR (BE2) (KIH) (VS-0622-YF8015)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
- Recombinant Human Anti-USP28 Soluble TCR (BA3) (KIH) (VS-0622-YF8014)
-
- Species Reactivity: Human
- Epitope: LIIPCIHLI
- MHC: HLA-A2
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For Research Use Only. Not For Clinical Use.