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VANGL1
This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Low cell line specificity
Interaction
Heterodimer with VANGL2. Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction (By similarity).
More Types Infomation
- Rabbit Anti-VANGL1 Polyclonal Antibody (MRO-2265-CN) (MRO-2265-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.