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VSIG4

This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
Protein class

Plasma proteins

Predicted location

Membrane

Single cell type specificity

Group enriched (Hofbauer cells, Kupffer cells, Macrophages)

Immune cell specificity

Group enriched (classical monocyte, myeloid DC, intermediate monocyte)

Cell line specificity

Not detected

More Types Infomation

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