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ZMPSTE24
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Molecular function
Hydrolase, Metalloprotease, Protease
More Types Infomation
- Recombinant Anti-human ZMPSTE24 Antibody (MOB-1057)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
- Recombinant Anti-human ZMPSTE24 Antibody scFv Fragment (MOB-1057-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IF, Neut, FuncS
- Recombinant Anti-human ZMPSTE24 Antibody Fab Fragment (MOB-1057-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, IP, FuncS
- Recombinant Human Anti-human ZMPSTE24 Antibody Fab Fragment (MHH-1057-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: RIA, IF, FuncS
- Recombinant Human Anti-human ZMPSTE24 Antibody scFv Fragment (MHH-1057-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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For Research Use Only. Not For Clinical Use.