This immunotoxin was achieved by conjugating/fusing the transferrin to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to TFRC expressing cells and enters cells by receptor-mediated endocytosis, then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treatment of T cell leukemias or lymphomas, graft-versus-host diseases, and autoimmune diseases.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G067E | Anti-TFRC immunotoxin HB21 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G067D | Anti-TFRC immunotoxin HB21 (scFv)-DT | Cytotoxicity assay, Function study | |
AGTO-G067G | Anti-TFRC immunotoxin HB21 (scFv)-Gel | Cytotoxicity assay, Function study | |
AGTO-G067R | Anti-TFRC immunotoxin HB21 (scFv)-RTA | Cytotoxicity assay, Function study | |
AGTO-G067S | Anti-TFRC immunotoxin HB21 (scFv)-Sap | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0464CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0464CL) | FuncS | Mouse IgG |
TAB-0465CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0465CL) | FuncS | Mouse IgG |
TAB-0466CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0466CL) | FuncS | Mouse IgG |
TAB-0464CL-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-0464CL-F(E)) | FuncS | Mouse Fab |
TAB-0465CL-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-0465CL-F(E)) | FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-611CT | Humanized Anti-TFRC Recombinant Antibody (TAB-611CT) | ELISA | Humanized IgG |
TAB-612CT | Humanized Anti-TFRC Recombinant Antibody (TAB-612CT) | ELISA | Humanized IgG |
TAB-613CT | Humanized Anti-TFRC Recombinant Antibody (TAB-613CT) | ELISA | Humanized IgG |
TAB-614CT | Humanized Anti-TFRC Recombinant Antibody (TAB-614CT) | ELISA | Humanized IgG |
TAB-611CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-611CT-S(P)) | ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-619CT-F(E) | Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-619CT-F(E)) | ELISA, WB | Human Fab |
TAB-620CT-F(E) | Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-620CT-F(E)) | ELISA, WB | Human Fab |
TAB-621CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (LUCA31) | ELISA, WB, FC | Human antibody |
TAB-623CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (3TF12) | WB | Human antibody |
TAB-624CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (3TF2) | WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1999CQ | Rat Anti-Tfrc Recombinant Antibody (clone RI7217) | FC, ICC, IP, WB, Block | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3548 | Rabbit Anti-TFRC Recombinant Antibody (clone DS3548AB) | FC, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC3370 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTGKL) MHC Tetramer | FCM | |
MHC-LC3371 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTG) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0376-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0376-CN) | ELISA, FC | Mouse IgG |
HPAB-0377-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0377-CN) | ELISA, FC | Mouse IgG |
HPAB-0378-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0378-CN) | ELISA, FC | Mouse IgG |
HPAB-0379-CN | Human Anti-TFRC Recombinant Antibody (HPAB-0379-CN) | ELISA, FC | Humanized IgG |
HPAB-0380-CN | Mouse Anti-TFRC Recombinant Antibody (clone BA120G) | ELISA, FC, IF, IP | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0238-YJ-F(E) | Rat Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0238-YJ-F(E)) | IHC, FC, WB, FuncS | Rat Fab |
HPAB-0239-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0239-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
HPAB-0240-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0240-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
HPAB-2624LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2624LY-F(E)) | ELISA | Mouse Fab |
HPAB-2692LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2692LY-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2702LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2702LY-S(P)) | ELISA | Mouse scFv |
HPAB-2703LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2703LY-S(P)) | ELISA | Mouse scFv |
HPAB-2704LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2704LY-S(P)) | ELISA | Mouse scFv |
HPAB-2705LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2705LY-S(P)) | ELISA | Mouse scFv |
HPAB-AP469-YC-S(P) | Human Anti-TFRC Recombinant Antibody (clone c5D7); scFv Fragment | FC, WB, Cyt, Inhib, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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