APC-A1/Human PCNA (ITEDMGHLKY) MHC Tetramer (CAT#: MHC-LC3417)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PCNA of peptide ITEDMGHLKY and A1 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A1
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PCNA
  • Antigen Species
  • Human
  • Peptide
  • ITEDMGHLKY
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
  • Alternative Names
  • PCNA; proliferating cell nuclear antigen; ATLD2

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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