Recombinant Mouse Anti-FMDV VP1 pentadecapeptide (YTTSTRGDLAHVTAT) Antibody (4C4) (CAT#: PABZ-047)

Figure 1 Neutralisation by antibody 4C4 fragments.

The molar amounts of MAb Fab2 and Fab are indicated on the abscissa.

Verdaguer, N., Schoehn, G., Ochoa, W. F., Fita, I., Brookes, S., King, A., ... & Hewat, E. A. (1999). Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation. Virology, 255(2), 260-268.

Figure 2 Absorbance vs. concentration plots obtained in the competition ELISA analysis of peptides A15 and A15S30.

Gomes, P., Giralt, E., & Andreu, D. (2000). Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants. Molecular immunology, 37(16), 975-985.

Figure 3 Correlation between thermodynamic affinity constant K_D and rate dissociation constant k_d for the interactions between peptides containing combinations of the mutations Ala138"Thr, Ala140"Thr, Leu147"Val, T149"Ala and mAbs SD6 (slope=3×10−5 , r2=0.98), 4C4 (slope=4×10−6 , r2=0.99) and 3E5 (slope=3×10−6 , r2=0.92).

Gomes, P., Giralt, E., & Andreu, D. (2000). Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants. Molecular immunology, 37(16), 975-985.