Recombinant Mouse Anti-HIV-1 Antibody (A10F9) (CAT#: PABX-089)

Anti-HIV-1 antibody (A10F9) is a mouse antibody of IgG class that binds to an HIV-1.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA

Figure 1 SDS-PAGE and western blotting of the assembled CA N21C/A22C-V3.

Figure 1 SDS-PAGE and western blotting of the assembled CA N21C/A22C-V3.

Lane M, molecular weight marker; lane 1, protein before assembly; lane 2-5, protein after assembly. The primary antibody is a CA specific mAb A10F9.

Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.

Figure 2 Antigenicity of CA N21C/A22C-V3 was determined with the A10F9 mAb using indirect ELISA.

Figure 2 Antigenicity of CA N21C/A22C-V3 was determined with the A10F9 mAb using indirect ELISA.

Data were analyzed by GraphPad Prism software. The 50% maximal effective concentration (EC50) was calculated by a four-parameter logistic fit, and is indicated in the square brackets.

Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.

Figure 3 Ribbon representation of a detailed view of p24 CTD recognition by the A10F9 Fab fragment.

Figure 3 Ribbon representation of a detailed view of p24 CTD recognition by the A10F9 Fab fragment.

The residues involved in protein-protein interactions are indicated and shown in stick mode.

Gu, Y., Cao, F., Wang, L., Hou, W., Zhang, J., Hew, C. L., ... & Xia, N. (2013). Structure of a novel shoulder-to-shoulder p24 dimer in complex with the broad-spectrum antibody A10F9 and its implication in capsid assembly. PloS one, 8(4), e61314.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native HIV-1
  • Species Reactivity
  • Human immunodeficiency virus 1
  • Clone
  • A10F9
  • Applications
  • Neut (assay-depended)
    FuncS (assay-depended)

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • Assay-depended

Target

  • Alternative Names
  • HIV-1; human immunodeficiency virus

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone A10F9"

See other products for "HIV-1"

Select a product category from the dropdown menu below to view related products.
Please select product type
Single-domain Antibody Humanized Antibody Immunotoxin Recombinant Antibody Fab Fragment Antibody Mouse Antibody Human Antibody Chimeric Antibody MHC Tetramer for Virology Rabbit Monoclonal Antibody scFv Fragment Antibody ADCC Enhanced Antibody
CAT Product Name Application Type
NAB-1889-sdAb Recombinant Anti-HIV-1 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH
PNBL-038 Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (PNBL-038) WB, FuncS Llama VHH

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for PABX-089. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare