Anti-Human ERBB3/ErbB 3 Recombinant Antibody (Seribantumab) (CAT#: TAB-892)
Recombinant humanized antibody expressed in CHO binding to human ERBB3. Seribantumab is used to treat cancer.
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ELISA
Figure 1 Anti-ERBB3 Recombinant Antibody (TAB-892) in ELISA
ELISA analysis of TAB-892 was performed by coating with human ERBB3 protein (2 µg/mL). Then blocked with BSA and incubated with TAB-892. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 5000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
WB
Figure 2 Anti-ERBB3 Recombinant Antibody (TAB-892) in WB
Western blot analysis of TAB-892 was performed with human ERBB3 protein in reduced condition Lane 1, Lane 2 and Lane 3 (0.1 μg, 0.3 μg and 0.6 μg, respectively) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-892 (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000). Chemiluminescent detection was performed.
DB
Figure 3 Anti-ERBB3 Recombinant Antibody (TAB-892) in DB
Dot Blot analysis of TAB-892 was performed by coating with human ERBB3 protein.
TAB-892 incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000)
NC: Negative Control PC: Positive Control
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- undefined
- Derivation
- Humanized
- Type
- IgG2 - lambda
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC, ICC
- CAS
- 1334296-12-6
- Generic Name
- Seribantumab
- MW
- 143.2 kDa
- Related Disease
- Breast cancers
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The ERBB3 antibody has been reported in applications of Inhib, Activ, WB.
Target
- Alternative Names
- Seribantumab;1334296-12-6;MM-121;SAR256212;ERBB3;v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian);LCCS2, lethal congenital contracture syndrome 2;receptor tyrosine-protein kinase erbB-3;HER3;proto-oncogene-like protein c-ErbB-3;tyrosine k
- Gene ID
- 2065
- UniProt ID
- P21860
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Seribantumab"
Afuco™ Anti-ERBB3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-892)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human ERBB3.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
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Customer Reviews and Q&As
Customer Review
Q&As
Laura Brown
Ideal for ERBB3 Research
Ideal for ERBB3 Research
The Anti-Human ERBB3 Therapeutic Antibody (Seribantumab) has been excellent for our ERBB3 research. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
03.Dec,23
Emily Lewis
Reliable in Immunoassays
Reliable in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for ERBB3 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
09.Aug,22
John Carter
Consistent and Effective
Consistent and Effective
This antibody has proven to be consistent and effective in our various assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for ERBB3 have been particularly beneficial.
26.Sep,21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-892, RRID: AB_3112016)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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