The TIM-3-specific antibody demonstrates potent and durable anti-tumor activity in syngeneic tumor models and therefore can be used for immunotherapy.
Figure 1 TSR-022 binding to native TIM-3.
TSR022 binding to monocytes that were purified from peripheral blood mononuclear cells (PBMCs) was confirmed.
Murtaza, A., Laken, H., Correia, J. D. S., McNeeley, P., Altobell, L., Zhang, J., ... & Jenkins, D. (2016). Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody. European Journal of Cancer, 69, S102.
Figure 2 MLR assay.
The functional activity of TSR-022 was also evaluated in a mixed lymphocyte reaction (MLR) assay, in which primary human CD4+ T-cells were mixed with monocyte-derived dendritic cells from a different donor.
Murtaza, A., Laken, H., Correia, J. D. S., McNeeley, P., Altobell, L., Zhang, J., ... & Jenkins, D. (2016). Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody. European Journal of Cancer, 69, S102.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-976 | Recombinant Anti-Tim-3 Antibody | WB, Neut, FuncS | IgG |
MHH-976 | Recombinant Human Anti-Tim-3 Antibody | ELISA, WB, FuncS | IgG |
VS-0723-WK188 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK188) | ELISA, FC | Rabbit IgG |
VS-0723-WK280 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK280) | ELISA, FC | Rabbit IgG |
VS-0723-WK289 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK289) | ELISA, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-976-F(E) | Recombinant Anti-Tim-3 Antibody Fab Fragment | FC, Neut, Funcs | Fab |
MHH-976-F(E) | Recombinant Human Anti-Tim-3 Antibody Fab Fragment | ELISA, WB, IP, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-976-S(P) | Recombinant Anti-Tim-3 Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
MHH-976-S(P) | Recombinant Human Anti-Tim-3 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0366CL-S(P) | Anti-Human TIM3 Recombinant Antibody scFv Fragment (TSR-022) | ELISA, WB | Human antibody |
TAB-0366CL-F(E) | Anti-Human TIM3 Recombinant Antibody Fab Fragment (TSR-022) | ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-665CT-S(P) | Anti-Human TIM-3 Recombinant Antibody scFv Fragment (F38-2E2) | ELISA, FC, Inhibit | |
TAB-666CT-S(P) | Anti-Human TIM-3 Recombinant Antibody scFv Fragment (mAb15) | ELISA, FC, Inhibit | |
TAB-667CT-S(P) | Mouse Anti-TIM3 Recombinant Antibody; scFv Fragment (TAB-667CT-S(P)) | ELISA, FC, Inhib | Mouse scFv |
TAB-668CT-S(P) | Mouse Anti-TIM3 Recombinant Antibody; scFv Fragment (TAB-668CT-S(P)) | ELISA, FC, Inhib | Mouse scFv |
TAB-669CT-S(P) | Mouse Anti-TIM3 Recombinant Antibody; scFv Fragment (TAB-669CT-S(P)) | ELISA, FC, Inhib | Mouse scFv |
There are currently no Customer reviews or questions for TAB-0366CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.