Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) (CAT#: Gly-087LC)

This product is a hypergalactosylated human monoclonal antibody with glycoslyated site in Fc region. The glycoengineered antibody Gal88-D2E7 has reduced anti-drug immune respone, it specifically binds TNFα and can be potentially used in the treatment of Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease and ulcerative colitis.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Glyco-engineering

  • Glycosylation site
  • Asn297 at Fc region
  • Glycoform (ratio)
  • G1F/G2F (88%)
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Reduced anti-drug immune response

Specifications

  • Target
  • TNFα (Tumor necrosis factor alpha)
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Antibody Isotype
  • IgG1
  • Clone
  • Gal88-D2E7
  • Applications
  • ELISA, FC

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor
  • Related Disease
  • Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease and ulcerative colitis

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Gal88-D2E7"

See other products for "TNF"

Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products Mouse Antibody Products Rat Antibody Products Humanized Antibody Products IgM Antibody Products Chimeric Antibody Products Single Domain Antibody Products Fc Glycosylation Antibody Products Non-hyper Galactosylated Antibody Products Sialylated IgG Glycan Products Hyper-galactosylated Antibody Products Chicken IgY Antibody Products Blocking Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products ScFv Antibody Products Antibody Magnetic Beads

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for Gly-087LC. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare