Recombinant monoclonal antibody to CD40. Selicrelumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
Figure 1 Assessment of TME by histopathologic and immunohistochemistry of the surgical resection specimen.
Representative images of Mason's trichrome staining from (A) treatment naïve cohort of UPenn patients or (B) patients treated with selicrelumab (Arm I). Red lines indicate the border of tumor regions. (C) Quantification of percent fibrosis in the TME for a set of untreated control PDAC resection samples and samples from Arm I and Arm II, as indicated.
Byrne, K. T., Betts, C. B., Mick, R., Sivagnanam, S., Bajor, D. L., Laheru, D. A., ... & Vonderheide, R. H. (2021). Neoadjuvant selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cancer. Clinical Cancer Research, 27(16), 4574-4586.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Afuco™ Anti-CD40 ADCC Recombinant Antibody (Selicrelumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD40. Selicrelumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G079E | Anti-CD40 immunotoxin G28-5 (scFv)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-126CL | Human Anti-CD40 Recombinant Antibody (TAB-126CL) | Block, Cyt, FuncS, Inhib | Human IgG |
TAB-200LC | Human Anti-CD40 Recombinant Antibody (TAB-200LC) | ELISA | Human IgG1, κ |
TAB-200LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-200LC-S(P)) | ELISA | Human scFv |
TAB-204LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-204LC-S(P)) | SPR, ELISA | Human scFv |
TAB-205LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-205LC-S(P)) | SPR, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-202LC | Anti-CD40 Recombinant Antibody (TAB-202LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG1 |
TAB-203LC | Anti-CD40 Recombinant Antibody (TAB-203LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG4 |
TAB-202LC-S(P) | Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-202LC-S(P)) | FC, ELISA | scFv |
TAB-203LC-S(P) | Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-203LC-S(P)) | FC, ELISA | scFv |
TAB-188LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-191LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-191LC-S(P)) | ELISA | Mouse scFv |
TAB-209LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-209LC-S(P)) | ELISA | Mouse scFv |
TAB-191LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-191LC-F(E)) | ELISA | Mouse Fab |
TAB-207LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-207LC-F(E)) | ELISA | Mouse Fab |
TAB-208LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-208LC-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-195LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-195LC-S(P)) | ELISA | Human scFv |
TAB-195LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-195LC-F(E)) | ELISA | Human Fab |
TAB-196LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-196LC-F(E)) | ELISA | Human Fab |
TAB-197LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-197LC-F(E)) | ELISA | Human Fab |
TAB-198LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-198LC-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-362CQ | Human Anti-CD40 Recombinant Antibody (clone 5D12) | Block, ELISA, FC, SPR, IP, IHC | Human IgG4, κ |
NEUT-363CQ | Mouse Anti-CD40 Recombinant Antibody (clone 5C3) | FC, Block, Activ | Mouse IgG1, κ |
NEUT-365CQ | Hamster Anti-CD40 Recombinant Antibody (clone HM40-3) | FC, Block, Costim, IHC | Hamster IgM |
NEUT-366CQ | Rat Anti-CD40 Recombinant Antibody (clone MAB0819) | Block, Activ | Rat IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-364CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL829) | WB, Neut | Mouse IgG2b, κ |
NEUT-367CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL013) | WB, IHC, Neut | Mouse IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4059 | Hi-Affi™ Rabbit Anti-CD40 Recombinant Antibody (clone SI126DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-105LC | Human Anti-CD40 Recombinant Antibody (MOB-105LC) | FC, FuncS | Human IgG1, κ |
MOB-106LC | Human Anti-CD40 Recombinant Antibody (MOB-106LC) | FC, FuncS, ELISA | Human IgG2, κ |
MOB-107LC | Human Anti-CD40 Recombinant Antibody (MOB-107LC) | FC, FuncS, ELISA | Human IgG2, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0162-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0162-YC) | FC | Human IgG |
HPAB-0163-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0163-YC) | FC | Human IgG |
HPAB-0164-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0164-YC) | FC, Agonist | Human IgG |
HPAB-0165-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0165-YC) | FC | Human IgG |
FN-133CQ | Rat Anti-CD40 Recombinant Antibody (clone CBL-1307) | Activ, Block | Rat IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0162-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0162-YC-S(P)) | FC | Human scFv |
HPAB-0163-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0163-YC-S(P)) | FC | Human scFv |
HPAB-0164-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0164-YC-S(P)) | FC, Agonist | Human scFv |
HPAB-0118-YJ-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0118-YJ-S(P)) | FuncS | Human scFv |
HPAB-1834-FY-F(E) | Human Anti-CD40 Recombinant Antibody (clone 21.4.1); scFv Fragment | Agonist, Activ | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-021CN | Human Anti-CD40 Recombinant Antibody (NS-021CN) | ELISA, IF, Block, FuncS | Human IgG |
NS-021CN-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (NS-021CN-F(E)) | ELISA | Human Fab |
NS-021CN-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (NS-021CN-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0009-WJ-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0009-WJ-F(E)) | ELISA | Human Fab |
HPAB-1662LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1662LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1663LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1663LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1664LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1664LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1665LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1665LY-F(E)) | ELISA, RIA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-152 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Dacetuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-262 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Teneliximab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
AFC-TAB-759 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Lucatumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-470CQ | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Selicrelumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-006ML | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Bleselumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1218WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1218WJ) | ELISA | Llama VHH |
HPAB-1219WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1219WJ) | ELISA | Llama VHH |
HPAB-1220WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1220WJ) | ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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