This transferrin specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities (KD=400 nM) for transferrin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-343 | Mouse Anti-TF Recombinant Antibody (clone 6A6) | WB, ELISA, IF, FuncS | Mouse IgG |
PABW-164 | Recombinant Mouse Anti-TF(Galβ1-3GalNAcα) Antibody (JAA-F11) | FuncS, IHC, FC, Cyt | IgG |
HPAB-2578LY | Human Anti-TF Recombinant Antibody (HPAB-2578LY) | ELISA | Humanized IgG |
HPAB-M0207-YC | Mouse Anti-TF Recombinant Antibody (HPAB-M0207-YC) | ELISA, Inhib | Mouse IgG |
HPAB-M0208-YC | Human Anti-TF Recombinant Antibody (HPAB-M0208-YC) | ELISA, Inhib | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-343 | Mouse Anti-TF Recombinant Antibody (clone 6A6); scFv Fragment | WB, ELISA, IF, FuncS | Mouse scFv |
PSBW-121 | Mouse Anti-TF Recombinant Antibody (clone 5G9); scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
PSBC-122 | Human Anti-TF Recombinant Antibody (clone hATR-5); scFv Fragment | Block | Humanized scFv |
FAMAB-0318CQ-S(P) | Mouse Anti-TF Recombinant Antibody (clone PTF.02); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1276WJ-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (HPAB-1276WJ-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0510CL | Mouse Anti-TF Recombinant Antibody (TAB-0510CL) | WB, IF, ELISA | Mouse IgG |
TAB-0510CL-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-0510CL-S(P)) | WB, IF, ELISA | Mouse scFv |
TAB-0510CL-F(E) | Mouse Anti-TF Recombinant Antibody; Fab Fragment (TAB-0510CL-F(E)) | WB, IF, ELISA | Mouse Fab |
TAB-598CT | Mouse Anti-TF Recombinant Antibody (TAB-598CT) | ELISA, FC | Mouse IgG1. κ |
TAB-598CT-F(E) | Mouse Anti-TF Recombinant Antibody; Fab Fragment (TAB-598CT-F(E)) | ELISA, FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-599CT | Anti-Human TF Recombinant Antibody (ATR-5) | ELISA, FC | Humanized antibody |
TAB-600CT | Anti-Human TF Recombinant Antibody (ATR-2) | ELISA, FC | Humanized antibody |
TAB-599CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (ATR-5) | ELISA, FC | Humanized antibody |
TAB-600CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (ATR-2) | ELISA, FC | Humanized antibody |
TAB-601CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (ATR-8) | ELISA, FC, BL | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-602CT | Anti-Human TF Recombinant Antibody (3e10) | ELISA, BL | Human antibody |
TAB-603CT | Anti-Human TF Recombinant Antibody (3h2) | ELISA, BL | Human antibody |
TAB-604CT | Anti-Human TF Recombinant Antibody (2c1) | ELISA, BL | Human antibody |
TAB-605CT | Anti-Human TF Recombinant Antibody (2c11) | ELISA, BL | Human antibody |
TAB-606CT | Anti-Human TF Recombinant Antibody (2d3) | ELISA, BL | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-175LC | Recombinant Anti-Human TF Antibody (Non-glycosylated) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0860MZ | Chicken Anti-Transferrin Polyclonal IgY | ELISA | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1996CQ | Mouse Anti-TF Recombinant Antibody (clone HTF-14) | WB, Neut, ELISA, ICC, IF, IHC, IHC-P, RIA | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2022CQ | Mouse Anti-TF Recombinant Antibody (clone A68-B/A11) | ELISA, Inhib, IHC-P, IHC-Fr | Mouse IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3535 | Rabbit Anti-TF Recombinant Antibody (clone DS3535AB) | IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0318CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone PTF.02); Fab Fragment | ELISA, FC | Mouse Fab |
FAMAB-0319CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone TW4.20); Fab Fragment | ELISA, WB, FC, Inhib | Mouse Fab |
HPAB-0232-YJ-F(E) | Rat Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0232-YJ-F(E)) | ELISA, FuncS | Rat Fab |
HPAB-0233-YJ-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0233-YJ-F(E)) | ELISA, FC, FuncS | Human Fab |
HPAB-2578LY-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-2578LY-F(E)) | ELISA | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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