This product is a recombinant mouse antibody that recognizes human APP. It may function in treating and/or preventing amyloid-beta associated diseases such as Alzheimer's disease.
Figure 1 The results of Biacore™ sensorgram overlays which shows the binding of BSA-conjugated linear or comprising the SNK epitope to linear (3F5, 3G2), cyclic (5E3, 5D8) and intermediate-specific (4D11, 4D12) monoclonal antibodies, and reactivity of these antibodies to synthetic Αβ 1-42 oligomers.
Figure 2 Results of static light scatter experiments to test Αβ polymerization in the presence ("5E3") or absence ("C") of antibody 5E3.
Figure 3 The results of a neuronal toxicity analysis which shows the degree of cell survival for cells incubated with a mock control, soluble monomeric and oligomeric Αβ 1 -40 in the presence and absence of 5E3 antibody at different concentrations.
Figure 4 Flow cytometry trace which shows the comparison of cells binding labelled 5E3 antibody and a negative control to the APP located at the cell surface.
Figure 5 The results of Biacore™ analysis which shows the binding to synthetic Αβ 1-42 oligomers to cyclic monoclonal antibody 5E3 at varying concentrations.
Figure 6 The results of Biacore™ sensorgram overlays which shows the binding of BSA-conjugated linear or comprising the SNK epitope to linear (3F5, 3G2), cyclic (5E3, 5D8) and intermediate-specific (4D11, 4D12) monoclonal antibodies, and reactivity of these antibodies to synthetic Αβ 1-42 oligomers.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1185z | Mouse Anti-APP Recombinant Antibody (clone 25F3) | WB, FC, ICC, IF, IHC | Mouse IgG1 |
PABL-010 | Mouse Anti-APP Recombinant Antibody (clone 12A11) | WB, IF, FuncS | Mouse IgG2a, κ |
PABL-011 | Mouse Anti-APP Recombinant Antibody (clone 3D6) | WB, ELISA, FuncS | Mouse IgG1 |
PABL-012 | Human Anti-APP Recombinant Antibody (clone 9TL) | WB, FuncS | Human IgG2, κ |
PABL-013 | Mouse Anti-APP Recombinant Antibody (clone C705) | WB, ELISA, FuncS | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-016 | Recombinant Anti-Human APP VHH Single Domain Antibody | CA, IP, IF, FuncS | Llama VHH |
PNBL-003 | Recombinant Anti-Human APP VHH Single Domain Antibody (PNBL-003) | WB, ELISA, FuncS | Llama VHH |
PNBL-004 | Recombinant Anti-Human APP VHH Single Domain Antibody (PNBL-004) | WB, ELISA, FuncS | Llama VHH |
PNBL-070 | Recombinant Anti-APP VHH Single Domain Antibody (PNBL-070) | ELISA, Neut, WB, Inhibition | Llama VHH |
TAB-0019CL-VHH | Camelid Anti-APP Recombinant Antibody (TAB-0019CL-VHH) | IHC, WB | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-226 | Anti-Human Abeta Recombinant Antibody (Crenezumab) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG4 - kappa |
TAB-0828CLV | Human Anti-APP Recombinant Antibody (TAB-0828CLV) | ELISA | Humanized antibody |
TAB-0829CLV | Human Anti-APP Recombinant Antibody (TAB-0829CLV) | ELISA | Humanized antibody |
TAB-0830CLV | Human Anti-APP Recombinant Antibody (TAB-0830CLV) | ELISA | Humanized antibody |
TAB-0831CLV | Human Anti-APP Recombinant Antibody (TAB-0831CLV) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-229 | Anti-Human Abeta Recombinant Antibody (Gantenerumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - kappa |
TAB-0343CL | Human Anti-APP Recombinant Antibody (TAB-0343CL) | ELISA, Inhib | Human IgG |
TAB-0344CL | Human Anti-APP Recombinant Antibody (TAB-0344CL) | ELISA | Human IgG |
TAB-0343CL-S(P) | Human Anti-APP Recombinant Antibody; scFv Fragment (TAB-0343CL-S(P)) | ELISA, FuncS, In vivo | Human scFv |
TAB-0815CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0815CLV-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-010 | Mouse Anti-APP Recombinant Antibody (clone 12A11); Fab Fragment | WB, IF, FuncS | Mouse Fab |
PFBL-011 | Mouse Anti-APP Recombinant Antibody (clone 3D6); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
PFBL-012 | Human Anti-APP Recombinant Antibody (clone 9TL); Fab Fragment | WB, FuncS | Human Fab |
PFBL-013 | Mouse Anti-APP Recombinant Antibody (clone C705); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
PFBW-009 | Mouse Anti-APP Recombinant Antibody (clone PFA1); Fab Fragment | ELISA | Mouse IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-254CQ | Human Anti-APP Recombinant Antibody (TAB-254CQ) | ELISA | Chimeric (mouse/human) IgG1 |
TAB-254CQ-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-254CQ-S(P)) | ELISA | Mouse scFv |
TAB-254CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-254CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
TAB-0789CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0789CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
TAB-0802CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0802CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0764CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0764CLV-S(P)) | ELISA | Mouse scFv |
TAB-0765CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0765CLV-S(P)) | ELISA | Mouse scFv |
TAB-0766CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0766CLV-S(P)) | ELISA | Mouse scFv |
TAB-0769CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0769CLV-S(P)) | ELISA | Mouse scFv |
TAB-0792CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0792CLV-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0685MZ | Chicken Anti-APP Polyclonal IgY | IHC | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-014 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204) | WB, ELISA, FuncS | Rabbit IgG |
PABX-014-F (E) | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204); Fab Fragment | WB, ELISA, FuncS | Rabbit Fab |
MOR-0220 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone DS220AB) | ELISA, WB | Rabbit IgG |
MOR-4539 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone TH47DS) | IHC-P, ELISA | Rabbit IgG |
MOR-0082-FY | Rabbit Anti-APP Recombinant Antibody (clone AFY0053) | ICC, IHC-P, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0566CQ | Mouse Anti-APP Recombinant Antibody (clone 6E10) | ELISA | Mouse IgG |
EPAF-0567CQ | Mouse Anti-APP Recombinant Antibody (clone 4G8) | ELISA, IHC | Mouse IgG2b |
EPAF-0568CQ | Human Anti-APP Recombinant Antibody (clone HyL5) | ELISA, Inhib | Human IgM |
EPAF-0569CQ | Mouse Anti-APP Recombinant Antibody (clone AB1-42) | IHC | Mouse IgG |
EPAF-0570CQ | Human Anti-APP Recombinant Antibody (clone L11.3) | IHC, ELISA, Inhib | Human IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-001CN | Human Anti-APP Recombinant Antibody (clone AS) | WB | Human IgG |
NS-007CN | Mouse Anti-APP Recombinant Antibody (NS-007CN) | ELISA, FuncS | Mouse IgG1 |
NS-001CN-F(E) | Human Anti-APP Recombinant Antibody (clone AS); Fab Fragment | WB | Human Fab |
NS-007CN-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (NS-007CN-F(E)) | ELISA | Mouse Fab |
NS-001CN-S(P) | Human Anti-APP Recombinant Antibody (clone AS); scFv Fragment | WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-225 | Afuco™ Anti-APP ADCC Recombinant Antibody (Bapineuzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-228 | Afuco™ Anti-APP ADCC Recombinant Antibody (Solanezumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-229 | Afuco™ Anti-APP ADCC Recombinant Antibody (Gantenerumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-227 | Afuco™ Anti-APP ADCC Recombinant Antibody (Ponezumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-226 | Afuco™ Anti-APP ADCC Recombinant Antibody (Crenezumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0732-FY-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0732-FY-F(E)) | DB, ELISA | Mouse Fab |
HPAB-0733-FY-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0733-FY-F(E)) | DB, ELISA | Mouse Fab |
HPAB-0735-FY-F(E) | Human Anti-APP Recombinant Antibody (clone H2L1); scFv Fragment | ELISA, FC, WB | Humanized scFv |
HPAB-S0005-YC-S(P) | Human Anti-APP Recombinant Antibody (clone ch3D6); scFv Fragment | ELISA, FuncS | Human scFv |
HPAB-1828-FY-F(E) | Mouse Anti-APP Recombinant Antibody (clone 2324); scFv Fragment | ELISA | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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